Yes.  When creating the event, the Event Manager(s) you assign will be the Event Manager(s) for all occurrences.  To change the Event Manager for a specific occurrence,  please follow the steps below:

1. Click on the Manage Tab 
2. Click Manage Events
3.  Search for the event occurrence you wish to change the Event Manager
4. Click on pencil to right of  the event name
5. Find and assign the Event Manager(s) you want  You can delete the original Event Manager(s) at this point
6. Click Save