1. Create two separate queries
2. Include the main group of records to keep in the first query
3. Include the group of records to be excluded in the second query
4. Select Tools, Merge from the menu bar
5. Select Query 1 as the Primary query
6. Select Query 2 as the Secondary query
7. Use the SUB operator to subtract Query 2 from Query 1
8. Save the Query with a new name