Other than screen resolution, Blackbaud does not have any requirements around these settings. While we could recommend using standard Windows defaults (such as a DPI of 96), we understand many users may need to adjust these settings. The Raiser's Edge, like other software programs that are outside of Blackbaud, are best viewed using the standard Windows defaults. When those defaults are altered, generally the view will change. The software does not adjust according the settings - the settings apply to everything viewed via the monitor.
For more information, view the Microsoft website regarding changing these settings back to the default options.
Note: We provide links to third-party websites in an effort to help you resolve your issue. We are not responsible for the information on third-party websites, and we cannot assist with implementing resolutions from these websites.