This can be accomplished by:
- Stop/Restart the Host on the server
- In Scheduler, choose File>Stop Host. Then, choose File>Start Host
- If the stop/start does not work, then complete the following on the server
- Go to Start>Run
- Type services.msc
- On this list, double click "Integration Service [your account id]"
- Click Stop
Now, go back to Scheduler, and you should be able to initiate a sync or send your mapping metadata. If not, Click Create a Case in the Additional Assistance box on the right. Reference this solution ID, and a support analyst will contact you.
If that doesn't resolve the issue, chat with Support and reference this article.