Error: Invalid column name 'MD5HASHCODE' when saving any transaction which requires a mapped designation

This error was reported in 2.93 after an update from patch 24 to patch 27. It occurs when attempting to add a payment which is tied to a designation such as a pledge.
This issue is caused by a faulty setting in the hosting applications manager. Please create a new case and include this knowledgebase number: BB736310

Environment

 2.93.2035.27

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