When making changes to the Business  contact information in Raisers Edge, the changes must be made on the Organization record, not from the Constituent or Organization Relationship records.  

To access the Organization record from the Constituent record:

1. Click on the Relationships tab
2. Right click the Organization, and select Open Organization Record
3. Make the necessary changes
4. Click Save and Close

Directory results should update immediately when saving the Raisers Edge record and  refreshing the page.