This error is related to a known issue with Windows Server 2003 and the SHA256 algorithm for SSL certificates. A hotfix for Windows Server 2003 was released to remedy this error and can be downloaded here. The hotfix must be installed on server used to host The Raiser's Edge.
Note: We provide links to third-party websites in an effort to help you resolve your issue. We are not responsible for the information on third-party websites, and we cannot assist with implementing resolutions from these websites.
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