If integration is run as a SQL job:

1. On the server that runs the integration, open SQL Server Management Studio.
2. Connect to the appropriate SQL Server instance.
3. Expand SQL Server Agent.
4. Expand Jobs. 
5. Highlight the PE/RE Integration Sync job.
6. Right-click and select Disable or Enable as needed.
Find out more about setting up the integration as an SQL job.

If integration is run as a scheduled task:

Refer to How to start/stop a scheduled task

Contact Patron Edge Support for further assistance integrating and/ or disabling the synchronization between Raiser's Edge and the Patron Edge.