To review the system roles and what permissions they give, read our Knowledgebase article on What system roles should I assign to Altru users? before adjusting a user's system roles profile. 

To add/edit security permissions (system roles) to the user: 
  1. Click Administration > Click Application Users
  2. Click the arrow beside the desired user > Click Edit
  3. Mark the checkboxes for the system roles the user needs
  4. Click Save